Killing vessels improves delivery
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چکیده
منابع مشابه
Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner
The blood vessels of cancerous tumours are leaky and poorly organized. This can increase the interstitial fluid pressure inside tumours and reduce blood supply to them, which impairs drug delivery. Anti-angiogenic therapies--which 'normalize' the abnormal blood vessels in tumours by making them less leaky--have been shown to improve the delivery and effectiveness of chemotherapeutics with low m...
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ژورنال
عنوان ژورنال: Nature Reviews Clinical Oncology
سال: 2011
ISSN: 1759-4774,1759-4782
DOI: 10.1038/nrclinonc.2010.209